Animal Viruses

A new Overlay for Plaquing Animal Viruses

Animal Viruses: Molecular Biology

In this multi-author work, Mettenleiter and Sobrino have compiled 10 chapters that describe what is currently known about the molecular biology of some of the most interesting viruses of veterinary importance, from the tiny circovirus of pigs (1,800 nt of single-stranded DNA) to the highly complex African swine fever virus (≈200,000 nt pairs of double-stranded DNA). It is fi tting that the fi r...

The budding mechanisms of enveloped animal viruses.

Some animal viruses mature from their host cells by budding out from the plasma membrane. In this process the virus nucleoprotein becomes enclosed within a plasma membrane vesicle, which is released into the extraceUular medium. The early work of Wecker 0957) showed that the phospholipids in the influenza virus membrane are derived from Pre-existing cellular phospholipids as would be expected f...

Are Animal Tumor Viruses Always Virus-Like?

Three tumors initiated by well characterized viruses, but in which virus is not detectable by ordinary virological techniques, are discussed. The question of the possible state of the virus within these seemingly non-infectious tumors is considered, largely from the standpoint of findings with the rabbit papilloma virus. This agent in its natural host, the cottontail rabbit, is infective, can b...

The production of interferon by animal viruses.

T he p roduc tion of in terfe ron b y an im al viruses is a response to th e v iral nucleic acid. A t high m u ltip lic ity of infection th e nucleic acid of th e infecting v irus is an adequa te stim ulus, w hile a t lower m ultip lic ities, v ira l nucleic acid synthesis is necessary for subsequent in te r­ feron fo rm ation . I t is n o t know n w hy v iral nucleic acids are such effective i...